Hypervitaminosis D, an uncommon reality!

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Adult Hypervitaminosis D-A Case Series

Prolonged hypervitaminosis D can result in calcium deposition in the soft tissues (especially the kidneys and heart), changes in the central nervous system & in severe cases, death. Patients and clinicians considering supplementation above currently recommended levels should be made aware of the possible toxicities of treatment with vitamin D, and baseline calcium and parathyroid hormone and vi...

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Neurofibromatosis, pathological fracture and hypervitaminosis-D.

Pathologic fractures in children may be due to various causes. Rarely, it may be the presenting symptom of neurofibromatosis. A misdiagnosis of Rickets and Vitamin D supplementation in such a case may wreak havoc in the form of iatrogenic hypervitaminosis D. We report one such case.

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Hypervitaminosis D associated with drinking milk.

BACKGROUND Vitamin D has been added to milk in the United States since the 1930s to prevent rickets. We report the unusual occurrence of eight cases of vitamin D intoxication that appear to have been caused by excessive vitamin D fortification of dairy milk. METHODS Medical records were reviewed and a dietary questionnaire was sent to eight patients who had unexplained hypervitaminosis D. Vit...

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Effects of Hypervitaminosis a and D on Skeletal Metabolism.

The feeding of escessive amounts of vitamin D to animals causes pathological changes in the skeleton and calcification of soft tissues (l-4). Hypervitaminosis A causes bone fragility. Spontaneous fractures occur in growing rats, whereas in the adult rat only rarefaction develops (5-8). Although excesses of each vitamin cause specific pathological changes, the concomitant feeding of toxic amount...

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Effect of alkali on metastatic calcification produced by hypervitaminosis D.

The effect of alkali (Sodium Bicarbonate) on metastatic calcification produced by Hypervitammosis D (ergocalciferol) was studied in rats. Six organs e.g. kidneys, heart, lungs, stomach, aorta and liver of the rats were examined for evidence of calcification. Six out of ten rats receiving vitamin D alone and seven out of ten rats receiving vitamin D and sodiumbicarbonate in combination, showed c...

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ژورنال

عنوان ژورنال: Endocrine Abstracts

سال: 2013

ISSN: 1479-6848

DOI: 10.1530/endoabs.31.p95